Smart Breath-Acuated Mesh Nebulizer
Advanced mesh nebulizer platform for combination product development, offering a wider range of customizable capabilities and features, which include breath actuation, Bluetooth connectivity, and activation mode.
THE ADHERESP SMART BREATH-ACTUATED MESH NEBULIZER
IS THE EXCEPTIONAL DELIVERY PLATFORM TO DEVELOP YOUR INHALED COMBINATION PRODUCT
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Breath Actuation
Suitable for children and adults (tidal breathing)
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Lock And Key
Activation system that allows the use of the device with a specific medication
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Easy To Clean
Practical design for dissembling to allow ease of cleaning
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Connectivity
Bluetooth connectivity for treatment data transmission
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Tactile And Visual Feedback
LED indicators and vibration feedback
DELIVER A WIDE RANGE OF FORMULATIONS, INCLUDING DIFFICULT-TO-DELIVER DRUGS SUCH AS BIOLOGICS AND SUSPENSIONS
Solutions1
Terbutaline Sulfate
5mg / 2ml
5mg / 2ml
Delivered dose: 88%
Delivery rate: 442 µg/min
MMAD: 3.47µm
FPF: 64.75±0.36%
Suspensions2
Fluticasone Propionate
2 mg / 2 ml
2 mg / 2 ml
Delivered dose: 72%
Delivery rate: 139 µg/min
DV50: 3.47µm
FPF: 69.13±4.06%
Biologics3
Interferon Beta-1b
0.15 mg / 1 ml
0.15 mg / 1 ml
Delivered dose: 86%
Delivery rate: 16.8 µg/min
DV50: 4.59µm
FPF: 55.93±1.46%
Sources
- Drug Delivery to the Lungs Conference. Volume 32, 2021: 119-122
- ONdrugDelivery. Issue 127, Nov. 2021: 38–41.
- Respiratory Drug Delivery 2022. Volume 1, 2022: 235-240.
WE OFFER AN INTEGRATED DEVELOPMENT PATH FOR YOUR DRUG-NEBULIZER DEVELOPMENT
Together We Develop the Optimal Drug-nebulizer Product for Your Inhaled Formulation, Using the Different Customization Levels of the AdheResp Platform
Hardware
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Indicators (visual, tactile, auditive)
PCB assembly
Reservoir fill volume
User Interface
Mesh
Mesh selection for pore size range
Firmware
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Triggering span
Liquid detection
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Activation count and length
Bluetooth connectivity
ADHERESP PLATFORM TECHNOLOGY
Mature and reliable mesh technology with palladium alloy mesh membranes
Bluetooth connectivity technology and NFC activation to monitor adherence
Flexible customization platform and professional advice for product development
We also support feasibility and customization aerosol performance studies in our state-of-the-art laboratories, including:
- Aerodynamic particle size distribution (cascade impactor)
- Droplet particle size distribution (laser diffraction particle size analyzer)
- Total drug substance delivered (breath simulator)
- Delivery rate and residue tests
AdheResp® Smart Breath-Actuated Mesh Nebulizer Video